The cover of the 7 May 2012 issue of the Journal of Experimental Medicine, featuring artwork by Lewis Long. Long’s artwork is based on Luk et al.’s findings  ”that injection of brain lysate from symptomatic aged mice into the brains of asymptomatic young mice is sufficient to initiate spreading of α-synuclein aggregates and to accelerate the onset of Parkinson’s disease–like symptoms. The original image shows α-synuclein (green) and microtubule-associated protein 2 (red) in the brain of a mouse injected 90 days prior with symptomatic brain lysate.”